CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | 4-hydroxy-tetrahydrodipicolinate synthase |
Enzyme Information
| 4.3.3.7 |
4-hydroxy-tetrahydrodipicolinate synthase.
based on mapping to UniProt P9WP25
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5- tetrahydro-(2S)-dipicolinate + H(2)O.
-!- Formerly EC 4.2.1.52.
|
UniProtKB Entries (1)
| P9WP25 |
DAPA_MYCTU
Mycobacterium tuberculosis H37Rv
4-hydroxy-tetrahydrodipicolinate synthase
|
PDB Structure
| PDB | 5J5D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues
Sci Rep
|