CATH Domain 5j40A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1050	Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
	1.20.1050.70	Large T antigen, SV40, domain 3

Domain Context

CATH Clusters

Superfamily	Large T antigen, SV40, domain 3
Functional Family

Enzyme Information

3.6.4.-

Acting on ATP; involved in cellular and subcellular movement.

based on mapping to UniProt P03072

UniProtKB Entries (1)

LT_POVJC

JC polyomavirus

Large T antigen

PDB Structure

PDB	5J40
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors. Bonafoux, D., Nanthakumar, S., Bandarage, U.K., Memmott, C., Lowe, D., Aronov, A.M., Bhisetti, G.R., Bonanno, K.C., Coll, J., Leeman, J., Lepre, C.A., Lu, F., Perola, E., Rijnbrand, R., Taylor, W.P., Wilson, D., Zhou, Y., Zwahlen, J., Ter Haar, E. J.Med.Chem.