CATH Classification

Domain Context

CATH Clusters

Superfamily Enolase-like C-terminal domain
Functional Family Enolase 1

Enzyme Information

4.2.1.11
Phosphopyruvate hydratase.
based on mapping to UniProt P09104
2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
-!- Also acts on 3-phospho-D-erythronate.

UniProtKB Entries (1)

P09104
ENOG_HUMAN
Homo sapiens
Gamma-enolase

PDB Structure

PDB 5IDZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma
Lin, Y.H., Satani, N., Hammoudi, N., Felini, F., Leonard, P.G., Maxwell, D., Link, T., Lee, G.R., Bosajou, A., Duoli, S., Marszalek, J.R., Sun, Y.T., McMurray, J., Mandal, P.J., DiFrancesco, M.E., Czako, B., Wang, A., Bornmann, W., DePinho, R.A., Muller, F.L.
To Be Published