CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Glutamate ionotropic receptor NMDA type subunit 2A

Enzyme Information

UniProtKB Entries (1)

Q05586
NMDZ1_HUMAN
Homo sapiens
Glutamate receptor ionotropic, NMDA 1

PDB Structure

PDB 5I2N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
Volgraf, M., Sellers, B.D., Jiang, Y., Wu, G., Ly, C.Q., Villemure, E., Pastor, R.M., Yuen, P.W., Lu, A., Luo, X., Liu, M., Zhang, S., Sun, L., Fu, Y., Lupardus, P.J., Wallweber, H.J., Liederer, B.M., Deshmukh, G., Plise, E., Tay, S., Reynen, P., Herrington, J., Gustafson, A., Liu, Y., Dirksen, A., Dietz, M.G., Liu, Y., Wang, T.M., Hanson, J.E., Hackos, D., Scearce-Levie, K., Schwarz, J.B.
J.Med.Chem.