CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DDX19B

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt A6ZNQ1
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

A6ZNQ1
DBP5_YEAS7
Saccharomyces cerevisiae YJM789
ATP-dependent RNA helicase DBP5

PDB Structure

PDB 5ELX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Pi Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5).
Wong, E.V., Cao, W., Voros, J., Merchant, M., Modis, Y., Hackney, D.D., Montpetit, B., De La Cruz, E.M.
J.Mol.Biol.