CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Triggering receptor expressed on myeloid cells 2 |
Enzyme Information
UniProtKB Entries (1)
| Q9NZC2 |
TREM2_HUMAN
Homo sapiens
Triggering receptor expressed on myeloid cells 2
|
PDB Structure
| PDB | 5ELI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.
Elife
|
