CATH Domain 5d7gG01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	Autophagy related 5

Enzyme Information

UniProtKB Entries (1)

ATG5_HUMAN

Homo sapiens

Autophagy protein 5

PDB Structure

PDB	5D7G
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. Kim, M., Sandford, E., Gatica, D., Qiu, Y., Liu, X., Zheng, Y., Schulman, B.A., Xu, J., Semple, I., Ro, S.H., Kim, B., Mavioglu, R.N., Tolun, A., Jipa, A., Takats, S., Karpati, M., Li, J.Z., Yapici, Z., Juhasz, G., Lee, J.H., Klionsky, D.J., Burmeister, M. Elife