CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Transitional endoplasmic reticulum ATPase

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt P55072
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

Q92890
UFD1_HUMAN
Homo sapiens
Ubiquitin recognition factor in ER-associated degradation protein 1

PDB Structure

PDB 5C1B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions.
Hanzelmann, P., Schindelin, H.
Structure