CATH Domain 5b71D02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

CO5_HUMAN

Homo sapiens

Complement C5

PDB Structure

PDB	5B71
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases. Fukuzawa, T., Sampei, Z., Haraya, K., Ruike, Y., Shida-Kawazoe, M., Shimizu, Y., Gan, S.W., Irie, M., Tsuboi, Y., Tai, H., Sakiyama, T., Sakamoto, A., Ishii, S., Maeda, A., Iwayanagi, Y., Shibahara, N., Shibuya, M., Nakamura, G., Nambu, T., Hayasaka, A., Mimoto, F., Okura, Y., Hori, Y., Habu, K., Wada, M., Miura, T., Tachibana, T., Honda, K., Tsunoda, H., Kitazawa, T., Kawabe, Y., Igawa, T., Hattori, K., Nezu, J. Sci Rep