CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Glutamate receptor ionotropic, kainate 2

Enzyme Information

UniProtKB Entries (1)

P19491
GRIA2_RAT
Rattus norvegicus
Glutamate receptor 2

PDB Structure

PDB 4X48
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Discovery and Characterization of the alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Potentiator N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242).
Shaffer, C.L., Patel, N.C., Schwarz, J., Scialis, R.J., Wei, Y., Hou, X.J., Xie, L., Karki, K., Bryce, D.K., Osgood, S.M., Hoffmann, W.E., Lazzaro, J.T., Chang, C., McGinnis, D.F., Lotarski, S.M., Liu, J., Obach, R.S., Weber, M.L., Chen, L., Zasadny, K.R., Seymour, P.A., Schmidt, C.J., Hajos, M., Hurst, R.S., Pandit, J., O'Donnell, C.J.
J.Med.Chem.