CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Macrophage colony-stimulating factor 1 receptor

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P07333
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P07333
CSF1R_HUMAN
Homo sapiens
Macrophage colony-stimulating factor 1 receptor

PDB Structure

PDB 4WRL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Felix, J., De Munck, S., Verstraete, K., Meuris, L., Callewaert, N., Elegheert, J., Savvides, S.N.
Structure