CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P04406
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.
2.6.99.-
Transferring other nitrogenous groups.
based on mapping to UniProt P04406

UniProtKB Entries (1)

P04406
G3P_HUMAN
Homo sapiens
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 4WNI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA.
White, M.R., Khan, M.M., Deredge, D., Ross, C.R., Quintyn, R., Zucconi, B.E., Wysocki, V.H., Wintrode, P.L., Wilson, G.M., Garcin, E.D.
J.Biol.Chem.