CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family

Enzyme Information

3.2.1.46
Galactosylceramidase.
based on mapping to UniProt P54818
D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
-!- Cf. EC 3.2.1.62.

UniProtKB Entries (1)

P54818
GALC_MOUSE
Mus musculus
Galactocerebrosidase

PDB Structure

PDB 4UFL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Chem.Sci.