CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase MSS116, mitochondrial

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P15424
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P15424
MS116_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase MSS116, mitochondrial

PDB Structure

PDB 4TYN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
Elife