CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

4.1.2.13
Fructose-bisphosphate aldolase.
based on mapping to UniProt W8TRN9
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
-!- Also acts on (3S,4R)-ketose 1-phosphates. -!- The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc. -!- Formerly EC 4.1.2.7.

UniProtKB Entries (1)

W8TRN9
W8TRN9_STAAU
Staphylococcus aureus
Fructose-1,6-bisphosphate aldolase

PDB Structure

PDB 4TO8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Characterization of Methicillin-Resistant Staphylococcus aureus's Class IIb Fructose 1,6-Bisphosphate Aldolase.
Capodagli, G.C., Lee, S.A., Boehm, K.J., Brady, K.M., Pegan, S.D.
Biochemistry