CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Thymidylate kinase |
Enzyme Information
| 2.7.4.9 |
dTMP kinase.
based on mapping to UniProt O67099
ATP + dTMP = ADP + dTDP.
|
UniProtKB Entries (1)
| O67099 |
KTHY_AQUAE
Aquifex aeolicus VF5
Thymidylate kinase
|
PDB Structure
| PDB | 4S2E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural studies of a hyperthermophilic Thymidylate Kinase enzyme reveal conformational sub-states along the reaction coordinate
Febs J.
|