CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol (PI) phosphodiesterase
Functional Family 1-phosphatidylinositol phosphodiesterase precurosr

Enzyme Information

4.6.1.13
Phosphatidylinositol diacylglycerol-lyase.
based on mapping to UniProt P45723
1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol.
-!- This enzyme is bacterial. -!- Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11. -!- Formerly EC 3.1.4.10.

UniProtKB Entries (1)

P45723
PLC_STAAE
Staphylococcus aureus subsp. aureus str. Newman
1-phosphatidylinositol phosphodiesterase

PDB Structure

PDB 4RV3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion.
He, T., Gershenson, A., Eyles, S.J., Lee, Y.J., Liu, W.R., Wang, J., Gao, J., Roberts, M.F.
J.Biol.Chem.