CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family receptor-type tyrosine-protein phosphatase delta isoform X2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt F1NWE3
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

F1NWE3
PTPRS_CHICK
Gallus gallus
Receptor-type tyrosine-protein phosphatase S

PDB Structure

PDB 4PBV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Coles, C.H., Mitakidis, N., Zhang, P., Elegheert, J., Lu, W., Stoker, A.W., Nakagawa, T., Craig, A.M., Jones, E.Y., Aricescu, A.R.
Nat Commun