CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Membrane-bound lytic murein transglycosylase F

Enzyme Information

4.2.2.n1
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt Q9HXN1
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

Q9HXN1
MLTF_PSEAE
Pseudomonas aeruginosa PAO1
Membrane-bound lytic murein transglycosylase F

PDB Structure

PDB 4OZ9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of MltF from Pseudomonas aeruginosa complexed with isoleucine
Reddem, E., Thunnissen, A.M.W.H.
To Be Published