CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

P01116
RASK_HUMAN
Homo sapiens
GTPase KRas

PDB Structure

PDB 4NMM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
Hunter, J.C., Gurbani, D., Ficarro, S.B., Carrasco, M.A., Lim, S.M., Choi, H.G., Xie, T., Marto, J.A., Chen, Z., Gray, N.S., Westover, K.D.
Proc.Natl.Acad.Sci.USA