CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family probable ATP-dependent RNA helicase DDX23

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q9BUQ8
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9BUQ8
DDX23_HUMAN
Homo sapiens
Probable ATP-dependent RNA helicase DDX23

PDB Structure

PDB 4NHO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.
Mohlmann, S., Mathew, R., Neumann, P., Schmitt, A., Luhrmann, R., Ficner, R.
Acta Crystallogr.,Sect.D