CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family

Enzyme Information

3.4.24.75
Lysostaphin.
based on mapping to UniProt P10547
Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans.
-!- Lyses cells of Staphylococcus aureus in particular, by its action on the cross-bridge of the cell wall. -!- Belongs to peptidase family M23.

UniProtKB Entries (1)

P10547
LSTP_STASI
Staphylococcus simulans
Lysostaphin

PDB Structure

PDB 4LXC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
Febs J.