CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

P01116
RASK_HUMAN
Homo sapiens
GTPase KRas

PDB Structure

PDB 4LPK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.
Nature