CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P21372
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P21372
PRP5_YEAST
Saccharomyces cerevisiae S288C
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

PDB Structure

PDB 4LJY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly.
Zhang, Z.M., Yang, F., Zhang, J., Tang, Q., Li, J., Gu, J., Zhou, J., Xu, Y.Z.
Cell Rep