1 keywords

CATH Domain 4kv5F00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 18-36

Enzyme Information

UniProtKB Entries (1)

P01137
TGFB1_HUMAN
Homo sapiens
Transforming growth factor beta-1 proprotein

PDB Structure

PDB 4KV5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of a pan-specific antagonist antibody complexed to different isoforms of TGF beta reveal structural plasticity of antibody-antigen interactions.
Moulin, A., Mathieu, M., Lawrence, C., Bigelow, R., Levine, M., Hamel, C., Marquette, J.P., Le Parc, J., Loux, C., Ferrari, P., Capdevila, C., Dumas, J., Dumas, B., Rak, A., Bird, J., Qiu, H., Pan, C.Q., Edmunds, T., Wei, R.R.
Protein Sci.