CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Ras family small GTPase

Enzyme Information

UniProtKB Entries (2)

Q5ZSM7
Q5ZSM7_LEGPH
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
LepB
P62820
RAB1A_HUMAN
Homo sapiens
Ras-related protein Rab-1A

PDB Structure

PDB 4IRU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism.
Mishra, A.K., Del Campo, C.M., Collins, R.E., Roy, C.R., Lambright, D.G.
J.Biol.Chem.