CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

UniProtKB Entries (2)

A7LCX1
A7LCX1_PIG
Sus scrofa
Interferon-induced helicase C domain-containing protein 1
P11207
V_PIV5
Simian virus 5 (strain W3)
Non-structural protein V

PDB Structure

PDB 4I1S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Motz, C., Schuhmann, K.M., Kirchhofer, A., Moldt, M., Witte, G., Conzelmann, K.K., Hopfner, K.P.
Science