CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family MHC class II H2-M beta 2 chain

Enzyme Information

UniProtKB Entries (1)

P13765
DOB_HUMAN
Homo sapiens
HLA class II histocompatibility antigen, DO beta chain

PDB Structure

PDB 4I0P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.
Guce, A.I., Mortimer, S.E., Yoon, T., Painter, C.A., Jiang, W., Mellins, E.D., Stern, L.J.
Nat.Struct.Mol.Biol.