CATH Classification

Domain Context

CATH Clusters

Superfamily Mur-like, catalytic domain
Functional Family UDP-N-acetylmuramate--L-alanine ligase

Enzyme Information

6.3.2.8
UDP-N-acetylmuramate--L-alanine ligase.
based on mapping to UniProt Q8ZIE8
ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP- N-acetyl-alpha-D-muramoyl-L-alanine.
-!- Involved in the synthesis of a cell-wall peptide.

UniProtKB Entries (1)

Q8ZIE8
MURC_YERPE
Yersinia pestis
UDP-N-acetylmuramate--L-alanine ligase

PDB Structure

PDB 4HV4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP
Halavaty, A.S., Minasov, G., Dubrovska, I., Winsor, J., Shuvalova, L., Peterson, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published