CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family

Enzyme Information

UniProtKB Entries (2)

P62826
RAN_HUMAN
Homo sapiens
GTP-binding nuclear protein Ran
P41920
YRB1_YEAST
Saccharomyces cerevisiae S288C
Ran-specific GTPase-activating protein 1

PDB Structure

PDB 4HB3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun, Q., Carrasco, Y.P., Hu, Y., Guo, X., Mirzaei, H., Macmillan, J., Chook, Y.M.
Proc.Natl.Acad.Sci.USA