CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Guanine nucleotide-binding protein G(k) subunit alpha

Enzyme Information

UniProtKB Entries (2)

Q8VDU0
GPSM2_MOUSE
Mus musculus
G-protein-signaling modulator 2
P08754
GNAI3_HUMAN
Homo sapiens
Guanine nucleotide-binding protein G(k) subunit alpha

PDB Structure

PDB 4G5O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
To be Published