CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

4.1.1.23
Orotidine-5'-phosphate decarboxylase.
based on mapping to UniProt O26232
Orotidine 5'-phosphate = UMP + CO(2).
-!- The enzyme from higher eukaryotes is identical with EC 2.4.2.10.

UniProtKB Entries (1)

O26232
PYRF_METTH
Methanothermobacter thermautotrophicus str. Delta H
Orotidine 5'-phosphate decarboxylase

PDB Structure

PDB 4FX8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Desai, B.J., Wood, B.M., Fedorov, A.A., Fedorov, E.V., Goryanova, B., Amyes, T.L., Richard, J.P., Almo, S.C., Gerlt, J.A.
Biochemistry