CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

2.8.2.36
Desulfo-A47934 sulfotransferase.
based on mapping to UniProt Q8KLM3
3'-phosphoadenylyl sulfate + desulfo-A47934 = adenosine 3',5'-bisphosphate + A47934.
-!- The enzyme from the bacterium Streptomyces toyocaensis catalyzes the final step in the biosynthesis of the glycopeptide antibiotic A47934, a naturally occurring antibiotic of the vancomycin group.

UniProtKB Entries (1)

Q8KLM3
STAL_STRTO
Streptomyces toyocaensis
Desulfo-A47934 sulfotransferase

PDB Structure

PDB 4EEC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of sulfonation of the glycopeptide antibiotic scaffold by the sulfotransferase StaL
Shi, R., Munger, C., Kalan, L., Sulea, T., Wright, G.D., Cygler, M.
Proc.Natl.Acad.Sci.USA