CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Vascular endothelial growth factor receptor 1

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P17948
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P17948
VGFR1_HUMAN
Homo sapiens
Vascular endothelial growth factor receptor 1

PDB Structure

PDB 4CL7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A
Gaucher, J.-F., Reille-Seroussi, M., Gagey-Eilstein, N., Broussy, S., Coric, P., Seijo, B., Lascombe, M.-B., Gautier, B., Liu, W.-Q., Huguenot, F., Inguimbert, N., Bouaziz, S., Vidal, M., Broutin, I.
Plos One