CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Glucan 1,4-alpha-glucosidase SusB

Enzyme Information

3.2.1.3
Glucan 1,4-alpha-glucosidase.
based on mapping to UniProt G8JZS4
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose.
-!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.

UniProtKB Entries (1)

G8JZS4
SUSB_BACTN
Bacteroides thetaiotaomicron VPI-5482
Glucan 1,4-alpha-glucosidase SusB

PDB Structure

PDB 3WFA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase
Okuyama, M., Yoshida, T., Hondoh, H., Mori, H., Yao, M., Kimura, A.
To be Published