CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family V-type proton ATPase catalytic subunit A

Enzyme Information

7.2.2.1
Na(+)-transporting two-sector ATPase.
based on mapping to UniProt Q08636
ATP + H(2)O + n Na(+)(Side 1) = ADP + phosphate + n Na(+)(Side 2).
-!- A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis. -!- The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). -!- Cf. EC 7.2.2.3 and EC 7.2.2.4. -!- Formerly EC 3.6.3.15.

UniProtKB Entries (1)

P43435
NTPD_ENTHA
Enterococcus hirae ATCC 9790
V-type sodium ATPase subunit D

PDB Structure

PDB 3VR6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Rotation mechanism of Enterococcus hirae V(1)-ATPase based on asymmetric crystal structures
Arai, S., Saijo, S., Suzuki, K., Mizutani, K., Kakinuma, Y., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S., Iwata, S., Yamato, I., Murata, T.
Nature