CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Ras-related C3 botulinum toxin substrate 1

Enzyme Information

UniProtKB Entries (1)

P63000
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1

PDB Structure

PDB 3TH5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Krauthammer, M., Kong, Y., Ha, B.H., Evans, P., Bacchiocchi, A., McCusker, J.P., Cheng, E., Davis, M.J., Goh, G., Choi, M., Ariyan, S., Narayan, D., Dutton-Regester, K., Capatana, A., Holman, E.C., Bosenberg, M., Sznol, M., Kluger, H.M., Brash, D.E., Stern, D.F., Materin, M.A., Lo, R.S., Mane, S., Ma, S., Kidd, K.K., Hayward, N.K., Lifton, R.P., Schlessinger, J., Boggon, T.J., Halaban, R.
Nat.Genet.