CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

O75581
LRP6_HUMAN
Homo sapiens
Low-density lipoprotein receptor-related protein 6

PDB Structure

PDB 3SOB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Bourhis, E., Wang, W., Tam, C., Hwang, J., Zhang, Y., Spittler, D., Huang, O.W., Gong, Y., Estevez, A., Zilberleyb, I., Rouge, L., Chiu, C., Wu, Y., Costa, M., Hannoush, R.N., Franke, Y., Cochran, A.G.
Structure