CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2300 | Response regulator |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.2300 |
| Functional Family |
Enzyme Information
| 2.8.4.2 |
Arsenate-mycothiol transferase.
based on mapping to UniProt P0DKS7
Arsenate + mycothiol = arseno-mycothiol + H(2)O.
-!- Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. -!- The product arseno-mycothiol is reduced by EC 1.20.4.3 (mycoredoxin) to arsenite and mycothiol-mycoredoxin disulfide. -!- Finally, a second mycothiol recycles mycoredoxin and forms mycothione.
|
UniProtKB Entries (1)
| P0DKS7 |
ARSC2_CORGL
Corynebacterium glutamicum ATCC 13032
Arsenate-mycothiol transferase ArsC2
|
PDB Structure
| PDB | 3RH0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms
Mol.Microbiol.
|
