CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family ISG15 ubiquitin-like modifier

Enzyme Information

UniProtKB Entries (2)

P05161
ISG15_HUMAN
Homo sapiens
Ubiquitin-like protein ISG15
P03502
NS1_INBLE
Influenza B virus (B/Lee/1940)
Non-structural protein 1

PDB Structure

PDB 3R66
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of the complex of ISG15 and Influenza B virus NS1 Protein: implications for the mechanism of SN1-mediated inhibition of ISG15 conjugation
Guan, R., Ma, L.C., Leonard, P.G., Brendan, A.R., Sridharan, H., Zhao, C., Krug, R.M., Montelione, G.T.
To be Published