CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase |
Enzyme Information
UniProtKB Entries (1)
| A4HWV2 |
A4HWV2_LEIIN
Leishmania infantum
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase
|
PDB Structure
| PDB | 3QW3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem.
|
