CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DBP5

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P20449
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P20449
DBP5_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase DBP5

PDB Structure

PDB 3PEW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Montpetit, B., Thomsen, N.D., Helmke, K.J., Seeliger, M.A., Berger, J.M., Weis, K.
Nature