CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.410 | Factor Xa Inhibitor |
|
4.10.410.10 | Pancreatic trypsin inhibitor Kunitz domain |
Domain Context
CATH Clusters
| Superfamily | Pancreatic trypsin inhibitor Kunitz domain |
| Functional Family | Pancreatic trypsin inhibitor |
Enzyme Information
UniProtKB Entries (2)
| P00974 |
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
|
| P35030 |
TRY3_HUMAN
Homo sapiens
Trypsin-3
|
PDB Structure
| PDB | 3P92 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.
Biochem.J.
|