CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family

Enzyme Information

UniProtKB Entries (1)

P21860
ERBB3_HUMAN
Homo sapiens
Receptor tyrosine-protein kinase erbB-3

PDB Structure

PDB 3P11
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Schaefer, G., Haber, L., Crocker, L.M., Shia, S., Shao, L., Dowbenko, D., Totpal, K., Wong, A., Lee, C.V., Stawicki, S., Clark, R., Fields, C., Lewis Phillips, G.D., Prell, R.A., Danilenko, D.M., Franke, Y., Stephan, J.P., Hwang, J., Wu, Y., Bostrom, J., Sliwkowski, M.X., Fuh, G., Eigenbrot, C.
Cancer Cell