CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin kappa chain variable 12-38 |
Enzyme Information
UniProtKB Entries (1)
| P00533 |
EGFR_HUMAN
Homo sapiens
Epidermal growth factor receptor
|
PDB Structure
| PDB | 3P0Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell
|