CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family dynamin-1 isoform X2

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt Q9UQ16
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

Q9UQ16
DYN3_HUMAN
Homo sapiens
Dynamin-3

PDB Structure

PDB 3L43
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the dynamin 3 GTPase domain bound with GDP
Yang, S., Tempel, W., Tong, Y., Nedyalkova, L., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H.
to be published