CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | pleckstrin homology domain-containing family M member 2 |
Enzyme Information
UniProtKB Entries (2)
| Q8IWE5 |
PKHM2_HUMAN
Homo sapiens
Pleckstrin homology domain-containing family M member 2
|
| Q56061 |
SIFA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Secreted effector protein SifA
|
PDB Structure
| PDB | 3HW2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis
J.Biol.Chem.
|