CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Killer cell immunoglobulin-like receptor

Enzyme Information

UniProtKB Entries (1)

P43632
KI2S4_HUMAN
Homo sapiens
Killer cell immunoglobulin-like receptor 2DS4

PDB Structure

PDB 3H8N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
Graef, T., Moesta, A.K., Norman, P.J., Abi-Rached, L., Vago, L., Older Aguilar, A.M., Gleimer, M., Hammond, J.A., Guethlein, L.A., Bushnell, D.A., Robinson, P.J., Parham, P.
J.Exp.Med.