CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase Fyn

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P06241
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P06241
FYN_HUMAN
Homo sapiens
Tyrosine-protein kinase Fyn

PDB Structure

PDB 3H0I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
SH3 domain specificity
Lugari, A., Ponchon, L., Hoh, F., Ktori, C., Ladbury, J.E., Strub, M.-P., Collette, Y., Morelli, X., Arold, S.T.
To be Published