CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family tRNA dimethylallyltransferase

Enzyme Information

2.5.1.75
tRNA dimethylallyltransferase.
based on mapping to UniProt P07884
Dimethylallyl diphosphate + adenine(37) in tRNA = diphosphate + N(6)- dimethylallyladenine(37) in tRNA.
-!- Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. -!- Formerly EC 1.8.6.1 and EC 2.5.1.8.

UniProtKB Entries (1)

P07884
MOD5_YEAST
Saccharomyces cerevisiae S288C
TRNA dimethylallyltransferase

PDB Structure

PDB 3EPJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism.
Zhou, C., Huang, R.H.
Proc.Natl.Acad.Sci.Usa